Boltz-1 Structure Prediction Benchmark
Evaluation suite accompanying Boltz-1 for full biomolecular complex prediction, comparing against AlphaFold 3 baseline on CASP-style metrics.
Composite
94.4
Experimental validation
Retrospective
Stages
Hit ID
Modalities
biologicsmall-molecule
Task types
structure-predictioncomplex-prediction
Size
complexes: 3,890
License
MIT
First release
2024-11
Last updated
2026-02
Official site
Leaderboard
Dataset
→ dataset
Code / GitHub
HuggingFace
→ HF
Paper
Boltz-1: Democratizing biomolecular interaction modeling · Passaro S, Corso G, et al. · 2024 · paper · doi:10.1101/2024.11.19.624167 · 120 citations
Flags
none
Experts
—
Groups
Hosted by
—
Related benchmarks
Rubric (7-criterion)
rigor
5
coverage
4
maintenance
5
adoption
5
quality
5
accessibility
5
industry_relevance
4
Notes
Open-source companion to commercial structure predictors; benchmark splits audited against AlphaFold 3 leakage.