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GuacaMol

Goal-directed + distribution-learning benchmarks for molecular generative models.
Composite score: 80.5

Rubric (1–5 per criterion)

rigor
4/5
coverage
4/5
maintenance
2/5
adoption
5/5
quality
4/5
accessibility
5/5
industry_relevance
4/5

Metadata

Stages
Lead ID / ADMETDevelopmental Candidate
Modalities
small-molecule
Task types
molecule-generation
License
MIT
First release
2019-03
Last updated
2022-07
Flags
none

Size & scope

Primary paper

Title
GuacaMol: Benchmarking Models for de Novo Molecular Design
Authors
Brown N, Fiscato M, Segler MHS, Vaucher AC
Year
2019
DOI / arXiv
10.1021/acs.jcim.8b00839
Citations
820

Links

Hosted by (initiatives)

Experts (primary authors / maintainers)

Groups (host labs / companies / consortia)

Related benchmarks

Notes (honest caveats)

First-generation generative benchmark; largely superseded by PMO for goal-directed.