PLINDER v2 Protein-Ligand Benchmark
Updated PLINDER with cleaner splits, biologic-ligand coverage, and per-assembly leakage audits. Industry-standard replacement for PDBbind/CASF for LLM-era docking.
Composite
97.0
Experimental validation
Retrospective
Stages
Hit ID
Modalities
small-moleculebiologic
Task types
dockingpose-predictionbinding-affinity
Size
complexes: 449,000
License
CC-BY-4.0
First release
2024-07
Last updated
2026-03
Official site
Leaderboard
Dataset
→ dataset
Code / GitHub
HuggingFace
→ HF
Paper
PLINDER: The protein-ligand interactions dataset and evaluation resource · Durairaj J, et al. · 2024 · paper · doi:10.1101/2024.07.17.603955 · 98 citations
Flags
none
Experts
—
Groups
Hosted by
Related benchmarks
Rubric (7-criterion)
rigor
5
coverage
5
maintenance
5
adoption
4
quality
5
accessibility
5
industry_relevance
5
Notes
PLINDER is consistently cited as the go-to replacement for PDBbind in modern docking evaluation.