CT-Open (Live Clinical Trial Outcome Benchmark)
Open-access, live, leakage-free platform for benchmarking clinical trial outcome prediction. Issues new time-stamped benchmarks quarterly via automated expert-validated pipelines. LLM-powered decontamination ensures outcomes weren't public at prediction time.
Composite
84.8
Experimental validation
Retrospective
Stages
phase-iiiphase-iphase-ii
Modalities
small-moleculetextclinical_data
Task types
clinical_trial_predictionoutcome_forecasting
Size
description: growing dataset
License
CC-BY-4.0
First release
2026-04
Last updated
2026-05
Official site
Leaderboard
Dataset
→ dataset
Code / GitHub
→ repository
HuggingFace
→ HF
Paper
CT-Open: A Live Clinical Trial Outcome Benchmark Without Leakage · · 2026 · paper · 2 citations
Flags
live_benchmarkleakage_freeclinical
Experts
—
Groups
—
Hosted by
—
Related benchmarks
Rubric (7-criterion)
rigor
5
coverage
3
maintenance
5
adoption
2
quality
5
accessibility
5
industry_relevance
5
Notes
Presented at ICLR 2026. Addresses critical data contamination problem in clinical trial prediction. Quarterly cadence: Winter/Spring/Summer/Fall challenges. Fully automated decontamination pipeline using iterative LLM web searches.