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Observed Antibody Space (OAS)

Repository of >1B antibody BCR sequences from public repertoires — core for antibody LM pretraining.
Composite score: 97.5

Rubric (1–5 per criterion)

rigor
5/5
coverage
5/5
maintenance
5/5
adoption
5/5
quality
4/5
accessibility
5/5
industry_relevance
5/5

Metadata

Stages
Hit IDLead ID / ADMET
Modalities
biologic-mab
Task types
antibody-sequence
License
CC-BY 4.0
First release
2018
Last updated
2025-04
Flags
none

Size & scope

Primary paper

Title
Observed Antibody Space: A diverse database of cleaned, annotated, and translated unpaired and paired antibody sequences
Authors
Olsen TH, Boyles F, Deane CM
Year
2022
DOI / arXiv
10.1002/pro.4205
Citations
310

Links

Hosted by (initiatives)

Experts (primary authors / maintainers)

Groups (host labs / companies / consortia)

Related benchmarks

Notes (honest caveats)

Underlies AbLang, IgLM, AntiBERTa — industry-adopted.