Open Systems Pharmacology / PK-Sim
OSP Suite — open PBPK/QSP models and validation sets.
Composite score: 80.3
Rubric (1–5 per criterion)
rigor
5/5
coverage
3/5
maintenance
4/5
adoption
3/5
quality
4/5
accessibility
5/5
industry_relevance
4/5
Metadata
Stages
Phase IIND-enabling
Modalities
small-moleculebiologic-mab
Task types
pbpk-validation
License
GPL-2.0
First release
2017
Last updated
2025-01
Flags
none
Size & scope
- models: 100
- validated_compounds: 50
Primary paper
Title
The Open Systems Pharmacology Suite: a new era in PBPK modeling
Authors
Lippert J, Burghaus R, Edginton A, et al.
Year
2019
DOI / arXiv
Citations
180
Links
- Official site: https://www.open-systems-pharmacology.org/
- GitHub: https://github.com/Open-Systems-Pharmacology
- Leaderboard: N/A
Hosted by (initiatives)
- not hosted by any tracked initiative
Experts (primary authors / maintainers)
Groups (host labs / companies / consortia)
Related benchmarks
Notes (honest caveats)
Open alternative to Simcyp.