Tox21
US Tox21 program HTS data on 12 nuclear receptor / stress response assays.
Composite score: 77.5
Rubric (1–5 per criterion)
rigor
4/5
coverage
3/5
maintenance
2/5
adoption
5/5
quality
4/5
accessibility
5/5
industry_relevance
4/5
Metadata
Stages
Lead ID / ADMETIND-enabling
Modalities
small-molecule
Task types
toxicity-classification
License
Public
First release
2014
Last updated
2017
Flags
none
Size & scope
- compounds: 10000
- assays: 12
Primary paper
Title
Tox21 Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways
Authors
Huang R, Xia M, et al.
Year
2016
DOI / arXiv
Citations
1100
Links
- Official site: https://tripod.nih.gov/tox21/
- GitHub: N/A
- Leaderboard: N/A
Hosted by (initiatives)
Experts (primary authors / maintainers)
Groups (host labs / companies / consortia)
Related benchmarks
Notes (honest caveats)
Field-standard tox benchmark; endpoint count small vs modern suites.