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USPTO-50K / USPTO-MIT (Retrosynthesis)

Reactions extracted from USPTO patents; standard retrosynthesis/forward-reaction benchmark.
Composite score: 78.0

Rubric (1–5 per criterion)

rigor
4/5
coverage
4/5
maintenance
2/5
adoption
5/5
quality
3/5
accessibility
5/5
industry_relevance
4/5

Metadata

Stages
Lead ID / ADMETDevelopmental Candidate
Modalities
small-molecule
Task types
retrosynthesisreaction-prediction
License
Public
First release
2017
Last updated
2023
Flags
data-leakage-known

Size & scope

Primary paper

Title
Neural Sequence-to-Sequence Models for Retrosynthesis Prediction
Authors
Liu B, Ramsundar B, Kawthekar P, et al.
Year
2017
DOI / arXiv
10.1021/acscentsci.7b00303
Citations
520

Links

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Experts (primary authors / maintainers)

Groups (host labs / companies / consortia)

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Notes (honest caveats)

Known leakage across canonical splits; use time-split or ORD for fairer eval.