DepMap (Cancer Dependency Map)
Genome-scale CRISPR/RNAi essentiality across 1150 cancer cell lines + omics.
Composite score: 100.0
Rubric (1–5 per criterion)
rigor
5/5
coverage
5/5
maintenance
5/5
adoption
5/5
quality
5/5
accessibility
5/5
industry_relevance
5/5
Metadata
Stages
Target IDDisease Modeling
Modalities
cross-modality
Task types
essentialitybiomarker
License
CC-BY 4.0
First release
2017-07
Last updated
2025-06
Flags
none
Size & scope
- cell_lines: 1150
- genes: 18000
Primary paper
Title
Defining a Cancer Dependency Map
Authors
Tsherniak A, Vazquez F, Montgomery PG, et al.
Year
2017
DOI / arXiv
Citations
2600
Links
- Official site: https://depmap.org/portal/
- GitHub: https://github.com/broadinstitute/depmap
- Leaderboard: https://depmap.org/portal/prediction/
Hosted by (initiatives)
- not hosted by any tracked initiative
Experts (primary authors / maintainers)
Groups (host labs / companies / consortia)
Related benchmarks
Notes (honest caveats)
Quarterly release cadence.