CZ Virtual Cell Challenge
Open challenge to predict transcriptomic responses to genetic & chemical perturbations across cell types, hosted by CZ Biohub.
Composite score: 88.1
Rubric (1–5 per criterion)
rigor
4/5
coverage
5/5
maintenance
5/5
adoption
4/5
quality
5/5
accessibility
4/5
industry_relevance
4/5
Metadata
Stages
Virtual CellTarget ID
Modalities
cross-modality
Task types
perturbation-prediction
License
CC-BY
First release
2024-11
Last updated
2025-09
Flags
none
Size & scope
- cells: 2000000
- perturbations: 300
Primary paper
Title
CZ Virtual Cell Challenge (launch)
Authors
CZI Science Team
Year
2024
DOI / arXiv
N/A — consortium launch
Citations
40
Links
- Official site: https://virtualcellchallenge.org/
- GitHub: https://github.com/czbiohub-sf
- Leaderboard: https://virtualcellchallenge.org/leaderboard
Hosted by (initiatives)
Experts (primary authors / maintainers)
Groups (host labs / companies / consortia)
Related benchmarks
Notes (honest caveats)
Gold standard-in-the-making for foundation-model era perturbation prediction. Hidden test → strong against leakage.