Stage: Disease Modeling
10 benchmarks, ranked by composite score. ← All stages
| # | Benchmark | Description | Modalities | Score | Flags |
|---|---|---|---|---|---|
| 1 | Open Targets Platform | Integrates genetic, genomic, pharmacological evidence to score targets for 20k+ diseases. | cross-modality | 100.0 | |
| 2 | DepMap (Cancer Dependency Map) | Genome-scale CRISPR/RNAi essentiality across 1150 cancer cell lines + omics. | cross-modality | 100.0 | |
| 3 | STRING | Protein-protein interaction & functional association network across 12k organisms. | protein-general | 94.9 | |
| 4 | PrimeKG | Precision medicine knowledge graph integrating 20 sources for 17k diseases. | cross-modality | 91.9 | |
| 5 | Longevity Benchmark (Insilico) | 19 aging/longevity benchmarks on ScienceAIBench/InsilicoBench/DDB — NHANES mortality, TCGA survival, methylation age, GTEx, Olink proteomic, longevity synergy. | cross-modality | 90.6 | |
| 6 | LINCS L1000 / CMap | 1.3M transcriptional profiles across 978 landmark genes after genetic or chemical perturbations. | small-moleculecross-modality | 89.9 | |
| 7 | TargetBench (Insilico) | 10 disease-area target identification benchmarks on ScienceAIBench/DDB (cancer, cardiovascular, endocrine/metabolic, fibrotic, inflammation/immunology, neuro, etc.). | cross-modality | 84.6 | |
| 8 | DisGeNET | Large collection of gene-disease associations (text-mining + curation + repositories). | cross-modality | 81.0 | license-gated-commercial |
| 9 | CPTAC Proteogenomic Benchmarks | Proteogenomic benchmarks across 10 tumor types — drives DREAM proteogenomic challenges. | cross-modality | 80.8 | |
| 10 | ClawBio Skill Correctness Bench | Third-party (Biostochastics LLC) benchmark of bio-analysis skills on safety / correctness / honesty. 10 skills × 182 tests. | cross-modality | 74.2 |